Dual speaker system

@elliottbnewcombjr now we are talking! So your first point is important  — does a second set of speakers affect the primary speakers? Looks like the answer is yes. 
 

My primary speakers are SF Amati paired with Mc 601s and I was thinking of a completely different second amp/speaker combo, but what if I added a Mc275 tube amp to the Amati and manually switched between the amps. That would be fun. Have you considered a speaker cable switch? I’d worry the switch would degrade SQ though.

@kota1 all same room!

@cptrips I”d be interested to hear more about how you are daisy chaining. I love the idea of two amps and two speakers and being able to switch between them all for different combinations 

To avoid a switch, I left a run of speaker cable from my speakers to a hook on the wall behind them that I could reach easily. Next, pull up the desired set of speaker wires from the desired amp (different colored tape on wire ends) and a spot of color tape on the front of each amp for feeble minded reminder.

wbt type bananas with set screws and center pin tightening

https://www.parts-express.com/Stacking-Banana-Plug-with-Dual-Set-Screws-Poly-Carbonate-Sh-091-3608?quantity=1

when using spades (connection at speakers/amps, I like the two set screw type

https://www.parts-express.com/5-16-Spade-Terminal-with-Dual-Set-Screws-and-Poly-Carbonate-091-3606?quantity=1

I have a similar situation and setup but (perhaps) for different reasons.

In my dedicated room I have my system on one side of the rack and a system for the family on the other side.  That way they don't mess with my stuff and dont use my speakers for movies.

My side Stream+SACD+DVDA-Allnic Pre-Manley+Threshold amps-Infinity IRS Beta

Their side Heos/stream-Denon ABR with DSP correction-Cambridge soundworks+Sunfire Subs

The HEOS also feeds Control4 for whole house

’best practice’ I said.

some audio shops roll each pair of speakers into a listening room so they are not exciting any others when you hear them.

yours in your space: play with both pairs adjacent as normal, fingers on the cones, any movement? then remove the inactive pair, any perceived difference?

If so, find a solution. If no perceived difference, you got lucky.

@elliottbnewcombjr In my application, the woofers on the Cambridge get excited with the IRS and vice versa but at a much lower level.  I have not found it to add coloring or become obstructing.