Your budget is good to get a great sounding system. Given your circumstances I would recommend starting from scratch… forget what you used to like. Use all the experience you gained on sound quality and components and start over.
I would start auditioning systems… locally first, then maybe a couple trips. Go listen to a Wilson system, a Sonus Faber system, Audio research, B&W, Magico, Conrad Johnson, Roland, Boulder… Magnaplanar. Don’t worry about cost. Find what connects to you.
Then start thinking about what to buy… speakers first.. but you have the advantage of getting all synergistic components at one time.
I found that carefully chosen component at each level sounds better than the last… so a $80K system will sound very significantly better than a $40K system and not nearly as good as a $160K.
I recommend buying the best you can and do not spend much on cables and interconnects (I buy DHLabs as really good quality budget wire), wait about six months or a year until all is broken in and you know what your system sounds like and then start working on optimizing your system with wire. You can then really compare speaker cables first, then power cord (amp)… then interconnects and finally interconnects for all your components. At the end of this… two or three years you can have an incredible system carefully customized to your own tastes.