Best Amplifier & Speakers combo?

If you get powered speakers they will be a perfect match.

1 percent time use for what that system?

@alexco17 

Why are you limiting yourself to these two combinations?

If you want the best at a given budget, why not list all your current equipment in the virtual equipment segment of this forum and provide a budget?

What will you do with the advice that you receive?  I ask because if you do the above you will get a diversity of suggestions.  How will you go from there?  Otherwise buy either of the ones that you suggested because few people here have heard both combinations and without hearing them, what value is their opinion?

Sound quality wise, CX81 and LS50 were better rated.  However, with LS50 priced at $1600, I will add a few hundreds and go with Buchardt S400 mk ii for its more extended frequency range (79hz-28khz -> 33hz-44khz ±3 dB).  LS50 is renowned for its midrange but S400 mk ii is not far away.  S400's extended, airy top end coupled with much more weighty and articulated low end enable you to enjoy music more.  You do not need sub for S400 either.

I would offer two suggestions.  1-Take the LS50 over the Q series, noticeable bump up in SQ IMO.  Both of my kids bought used LS50s and are very pleased. 2-The non-Meta KEF R3s are being discounted now and should be a strong consideration.  They will sound a bit fuller than the much smaller LS50s since they have a dedicated bass driver.  I'm sure they will do better with a bit more power which can be an upgrade down the line.  Good luck and cheers.