as a generality, kt66/6l6 tubes are basically a weaker (less powerful) el34 -- they will usually sound weaker/slower in the bass, and sometimes a touch more ’beautiful’ in a classic tubey manner in the lower treble, mids and upper bass
but obviously, tube makes within a type, can have sonic differences that may overwhelm that across tube types (a gec kt77 vs a shuguang el34 may would sound more different than a modern russian sovtek kt66 for instance)