Stated simply, my answer to your question would be to try as many different cables as you believe are necessary to satisfy your curiosity and budget, and then purchase and use the cables that you believe make your system sound its best.
At risk of losing my invitation to the audiophile Christmas party, I find this whole "loom" phrasing mildly amusing. A loom is a tool or machine for weaving. As a verb, it is used to describe something that appears large or threatening. Apparently, the term "full loom" describes the width of a cloth that is equal to the full width of the loom, which somehow morphed into a full complement of audio cables from a single manufacturer.
I suspect the marketing department of a cable company came up with the usage of "full loom" in relation to audio cables in order to encourage buyers to purchase every possible cable in their system from one source (i.e., their company) with the idea that having a single cable from another manufacturer would certainly spoil the gestalt and ruin any possibility of coherent sound from the afflicted system. The audiophile equivalent of a Jedi mind trick. Colonel Potter would call it, "horse hockey."
I can sort of understand the reasoning for matching all analog interconnects from a single manufacturer, but the idea that ICs relate to SCs, PCs, or digital cables, seems to be a stretch. I did not hear any specific sound quality benefit any of the times I used cables from only a single manufacturer.