Dog pissed on speaker

Maybe your dog can hear better than you and he is trying to tell you something - get rid of the speakers. 

Seriously here's what you need to do. Get a bowl of warm water and add a tablespoon of Arm & Hammer baking soda, stir it good then dampen a cloth with this solution, ring it out then gently wipe the area where the pee is. This will neutralize the pee (ammonia). The wipe again with clean water. Don't over do it.

Maddening, isn't it. Flipping cats(four)and dogs(three)like to go in the front room where I have my ping pong table. 

Only one person suggest an ozone generator.  Least likely to damage the components. That would eventually break down the uric acid, urea, and other nittrogenous compounds generating the ammoniacal smell after bacteria and enzyme exposure. UV light (germicidal) might work, but don't expose paper to it (no speaker cones) only the box.

Jeez, just replace the driver. Quick search showed OEM driver is under 150 $. I wouldn't think twice.