I never tried 6N6 sub in my Ref 6, but I remember this being discussed several years ago on other forums (WBF). It was warned these tubes will have a shorter than expected life in ARC preamps. 1,600 hours is likely way too much for them, and the 6550 should be replaced too at this point.
I got the impression 6N6 is being run very hard (beyond their specifications) in these circuits. The sub was also never sanctioned by ARC. You’re playing with fire.
Subs to the power tube are also possible - KT88, KT90 (you have to run with lid off due to tube height, but I was told this is a very good tube here) - also not officially sanctioned by ARC, though I haven’t heard any ominous warnings about that sub. In that case, you’re going to a more robust tube (don’t try a KT120 or anything that will draw more heater current, though). I personally used KT88 with no problem in Ref 6. But the stock tubes are good - and I agree with others, these circuits are just NOT made for tube rollers. I’d stick to 6N30 (aka 6H30) and try to compensate for the sonics elsewhere. Nice excuse to upgrade your DAC and cartridge :) I’m curious though, what did the 6N6 do that you liked better?
I guess if you're adventurous and want to continue the 6N6 ride...no more than 1000 hours max per set.