??? How Much Would You Spend ???

There doesn't have to be a specific price tag for a given pair of speakers. You could spend 10K on an amp for those speakers and a 5K amp might outperform it. There are too many variables to give a cookie cutter answer to this one.

I would buy used and spend 2 to 4k.  

My rule of thumb is 30% speakers, 15% preamp, 15% amp, 15% DAC and 15% streamer. Just a generality. If I was doing it I would be getting $10K components. This level gets you very top notch components that will sound great and last for decades. I just helped a friend do exactly what you are talking about. Using an Audio Research LS28 prevamp, a VT 80SE Amp. I would recommend an Audio Research DAC 9, and Aurrender N200 or better yet N20. Room treatments after setup. I could live with this system the rest of my life. Musical, natural, powerful, and detailed.

This assumes you want an all around musical system. If you want a “rock system” then Mac and B&W speakers, highly detailed and shiny Luxman and DynAudio. lots of “kinds” of sound.

I would spend around what I have in my bank account. Not more.

How big is the room?  Is it your primary system or a secondary system?