@czarivey Interesting question! I don't think it matters if you're facing speakers in a two-channel system or have them placed directly at your back. Your ears function as the receiver(s) of sound. As such, I would think the normal considerations for a two-channel sound system apply (i.e. room size & acoustics; speaker placement; listening distance from the speakers; sweet spot; etc.). That being said, if your seated or listening position is off axis (i.e. not directly in the center of both left & right channel, otherwise known as the sweet spot), you'll probably prefer speakers that have good "off axis response". If you intend to audition speakers in a good shop(s) before purchasing them, I recommend that you explain what you're after and have the shop(s) set up the room(s), speakers, etc., in as close to your home/office configuration as possible. I think most omnidirectional speakers might appeal to you but there are others, as well (e.g. Revel; PSB; Klipsch; etc.). Your ears will be the best judge.
Good Luck!