I'm not sure I would say "zero chance", because a) folks who exclusively listen to acoustic music at sensible volumes may be well served by single-drivers, and b) as @arafiq says, some single-drivers are said to outperform 3-way speakers. Lowther and Voxativ also come to mind, though tbh I've never auditioned either of them.
@devinplombier A friend of mine locally has been messing with 'full range drivers' for the last 25 years. I've heard a variety of them at his house and in my shop as a result. Most of them sound just fine as long as you don't push them too hard. All of them fall flat on their face if you try to play anything with energy (with bass in it) at higher volumes.
So I've heard Lowther, PHY, Voxitive, Fostex, Tangband and Cube; several different models from each brand.
If you really want to get the most out your investment in such drivers you'll make sure they don't have any bass excursion on them by using some kind of crossover. IME a better way to do that is by placing a small coupling cap in series with the input of the amp driving that speaker. That way the amp has the same benefit.