In general, my only concern about a DAC and pre-amp in a single box would be how well is the pre-amp section shielded from RFI generated by the digital circuits/DAC? In general, I would prefer these in separate boxes separated by space as an insurance policy at a minimum. I would definitley not try to cram a low level phono section in there as well.....
A similar concern with integrated amps is proximity of power amp with transformers, etc. to the pre-amp section, again especially with phono. HEre the issue is more EMI than RFI perhaps, but I would prefer separates here as well to physically separate the two as an insurance policy at minimum. Often, noise levels in circuits can affect the sound quality in subtle ways well before any effects are clearly audible.
A similar concern with integrated amps is proximity of power amp with transformers, etc. to the pre-amp section, again especially with phono. HEre the issue is more EMI than RFI perhaps, but I would prefer separates here as well to physically separate the two as an insurance policy at minimum. Often, noise levels in circuits can affect the sound quality in subtle ways well before any effects are clearly audible.