I believe in using one single maufacturer, although I consult with the owner of the cable manufacturing company regarding product application. My two channel system incorporates his top of the line cable for every application. My HT uses what I would consider a compromise, what the owner feels is "correct application", due to less revealing components, higher noise floor due to marginal power conditioning, less critical performance demand, etc.
I propose that many designers consider one specific element of design playing a higher level of importance to the completed product. Whether these specific elements are in regards to physical configuration, or inductance/capacitance, or shielding, or fit & finish, whatever. It is ultimately what the designer feels is a priority in their particular design criteria. Personally? I feel it is what creates that specific manufacturers "synergy" or "personality". I feel that this becomes evident when each individual manufacturer's cable displays different types of sonic characteristics. Whether those characteristics could be considered pleasing is a matter of personal preference.
The manufacturer I have chosen, places priority in quiet signal transfer. This is a specific element that he considers highly important. He firmly believes that the quieter the better. He also feels that there are many, many benefits to producing the absolute quietest cable possible to the best of his ability. Increased resolution, dynamic range, high definition sound stage are just some of the residual benefits. It shows.
Are there "better" sounding cable combinations available? Maybe.
Are there "different" sounding cable combinations available? Absolutely.
Are there "quieter" sounding cable combinations available? I doubt it.
But, if you find one, let me know.