The Prologue 2 is a great piece to start with. I have been using one for three years now very happily. The stock tubes are good, but the sound can be bettered with some tube rolling. Svetlana Winged C KT-88, Electro-Harmonix 6550, Svetlana Winged C EL-34, NOS Mullard 12AX7, NOS Sylvania 12AU7 will all do nicely.
I have used the PL2 with a number of speakers in both smaller and larger rooms. Some equipment that I can recommend:
Speakers
Rega R1 (monitors) - currently used with PL2
NHT SB3 (monitors)
Omega Super 3 (monitors)
Opera Platea (small floorstanders) - currently used with PL5
CD players
Rega Apollo - currently used with PL2
Music Hall CD25
Musical Fidelity A3.2 (now the A5) - currently used with the PL5
The PL2 runs hot, so it will need some room to breath. Other than that it is a very fuss free piece to own.
Regards, Rich