I'm 65 now but still in good shape. Still my 110 lb ayon amp is too heavy/awkward for me to move by myself. it is for sale. My decware is about 45 lbs. I'm having a new amp built. It will weigh about 120 lbs so we spit it into 2 chassis. I still like big transformers and chokes so it is hard to design those to be light.
On speakers, if you stick with box shaped speakers, it is pretty easy to move them around without actually picking them up. One of my hobbies is machining and I moved a 2500 lb lathe and 2000 lb mill into my garage by myself. Like an Egyptian. Let physics be your friend. But that is hard to do on a tube amp.
Jerry