Feel like I'm outta my mind....

2.2 is absolutely the way to go. 

Without getting stupid or too stupid here is where you should start.

Get a pair of Harbath P3's and put then on stands the get two Martin Logan 210 balanced force subwoofers and a MiniDSP SHD to run everything. This will out perform the vast majority of systems out there. Do not be fooled by their size. The limiting factor is always the tweeter power handling ability. The Tweeter in the P3 can and is used in much larger speakers. Small speakers are special because the enclosure is so small it disappears sonically leaving a pristine image. This system will have no trouble doing 110 dB in a medium sized room. Rock to your hearts content. 

Some suggestions above involve big dough.  So listen widely and think long and carefully.  So many here have said they bought an item and then changed it a short time afterwards.  As you're getting on in years (like me), I suggest viewing these changes as your 'forever system'.

Consider the size of your listening space before buying speakers.  Some need more breathing space than others.

If you’re going with dual subs (I think you should, as they eliminate any lumpy inconsistent base response throughout a room, unless it’s the size of an auditorium) then I suggest using high sensitivity speakers.

Dual subs generally eliminates the need for low lower sensitivity speakers, which dig deeper in bass response .

IME using high sensitivity mains and dual subs (properly crossed over) unloads the mains and allows you to enjoy much better effortlessness in sound, resulting in much cleaner and dynamic sound!

Hi,  I've had a lifetime's worth of speakers - more recently Sonus Faber, Quad, Canton, Magico (S1 2), Ktema, Monitor Audio Gold 300, etc. Fed up with them all in no time: the small Magico 'bite' and edginess, much the same for the MA 300s (no bass), while the Cantons 3Ks were simply boring and the Quads didn't like the humidity here. Of course, much of this has to do with system matching, but both myself and a now retired hifi dealer that I am great friends with have tried a huge array of gear. And not coincidentally, we have both ended up with speakers from far-off Lithuania:  AudioSolutions - the Figaro Ls in my case. No, they're not American or British, and they're not made in China; but they really 'dance'. Great tonality, sweet mid range, tremendous bass and as good a soundstage as the rest of the system allows. No, they're not world-beaters, but they are great for everything from Tool to Tord Gustavsen and Alice Sara Ott, and don't cost two arms and three legs. Put that down to a combination of old-fashioned, but also traditional, paper cones and very complex (and very dense) cabinet design. They are heavy and need a bit of room to breathe, but are a rare find in a world of insane hifi prices. Next step up would be Magico S5s, but I'm damned if I'm going to pay more than three times what I paid for my Figaros for a fractional gain. For what it's worth.