I am looking to upgrade - looking for advice

I agree with jasonborne on this one. If you stick with your current sources as is, it is very unlikely that a new set of amp/preamp will make big improvements. BTW, I love my A21+ amp.

I’m always amazed how many are devoted to the concept that spending (significantly) more money equals improved SQ. We all tend to agree that SQ is a perceptive concept, not an empirical one. Yet many espouse that the bigger hit to your credit card will automatically result in jaw dropping improvements. I respectfully and adamantly disagree. 
 

No one can tell you what to buy. Or what to spend to achieve your objectives. Only you can. Heck, most will suggest you buy what they have. Bottom line, your best bet is to try equipment of interest and decide for yourself. But don’t let the price tag be a basis for anticipated improvement. 
 

Sorry for being a grouch this morning. We ran out of coffee so I’m stuck with decaf. 

What is budget? 

Would you consider an integrated amplifier? 

Vincent makes a tube/SS hybrid integrated that has a DAC onboard. They also make a hybrid preamp that mates with the SP-332. I have owned a Vincent integrated and it sounded wonderful at the price point. Would sound less clinical, not as dry with more air, than the Rotel gear. Great soundstaging.

Another thought, given that streaming is your main source you might think about getting a DAC to pair with the Node. There are threads on this forum that address that option.  If your cd player has digital out the DAC could also serve it.

If you enjoy your B&W speakers keep them. There is much you can do to get more out of them.

Price range for all upgrades? Can't recommend an upgrade without knowing what you are comfortable spending

Everything starts with the source components.  I always attack my weak points first.  I would look into upgrading that streamer first.  Then see if that makes a diffo.  Lots of good streamers also have a decent DAC built in.