There are two issues you should think about when using a PC/laptop as a source. Galvanic isolation for the signal which I assume is USB, and the noise in the power supply.
You can solve the power supply noise issue by putting the PC on a different AC circuit, but then that causes digital ground loops and sometimes even audible hum via ground loops. If it's digital only it can cause excess jitter
Some DACs have excellent galvanic isolation on the USB port, some do not. Either way the solutions are cheap.
The big issue IMHO tends to be the power supply noise, which is of course is also the ground loop issue.
So, yes, get an inexpensive USB isolator but also be aware of where you plug the PC power into. If at all possible put it on a different circuit, and under no circumstances should you put it on the "clean" side of your power conditioners.