Some thoughts from my experiences with 300b.
I was curious about 300b tube sound. But they were never going to power my main system. So, instead I chose to have them power my headphone system. Turned out to be a great choice for me. This gave me a great opportunity to experience their fantastic sound. This lead to me completing upgrading my main system to all tubes.
This may be out of your price range but my 300b headphone amp can also be used as an integrated amp and drive speakers. Woo WA5-LE.
To get great tube sound out of speakers like you are considering, a used Audio Research I-50 would be a good choice. Not 300b, but warm and detailed with more power.