Getting back to the OPs point, yes, music can and does move me without the need of drugs. (Yes, I did smoke back in the day and drank beer to fool my parents. That was in the past and I begrudge no one here what they choose to do.)
I'm just not that high and mighty or condescending enough to pass judgement on anyone here.
Now it's just a half a glass of wine once a week or so. All it takes, for me, is to simply slip into the music when the connection is made and it's off to audio nirvana. By the way, I'd love to experience Joyce DiDonato from what I just read.