Newbie want to improve what I have

Totally agree with the room treatment thing. One look at my house of stereo system will show you that it is of the upmost importance to me. Another layer to this journey and the most important one if you are really serious about getting the absolute best sound you can. However the majority of audiophiles ignore that aspect. 

If I were you, I would PM John Rutan, his Audiogon Tag is 'Audioconnection'.

I promise you that he will give you the best advice and not try to sell you something.

FWIW,

I think you have some nice equipment. That you feel the need to change is understandable, but, as has been said before

'If it ain't broke, don't bother'

All of us 'audiophiles' want to move onto something 'better', but that depends (esp. those of us who don't have unlimited budgets), on what we can afford.

My 2 cents-

Ask yourself, what do you find deficient in your current system?

I say this as someone who came to high end stereo in the '80's, when there were lots of brick and mortar businesses to audition equipment. 

Unfortunately, today, unless you live in a major city, your options to audition are limited. If you are near a dealer, and can schedule an audition, then do so.

What you like is solely up to you.-But, in order to make that decision, you need to know/understand what your ears feel what sounds 'best'.

Please feel free to PM me.

Bob

If the M33 is plugged into the Isotek, unplug it from there and go wall outlet direct. Also have a decent gauge power cord for the M33. 14 gauge or thicker should be dandy. Do this and report back with any improvements or detriments. 

Sopra No.1s are one of my favorite 2ways ever. Congratulations on your purchase! The key with this sport is fitting the system to the room in terms of proximity to adjacent room boundaries, overall room volume, etc.  The normally rational Erik Squires above advises no toe-in without knowing about your room size, shape or where they fit in. Toe-in may be desirable depending on these factors. The best thing about your speakers and amp is their low coloration…If your music is well recorded you will hear it in its splendor. Warm is code for filtered. Do you want that?  Why invest in Purifi clean power and beryllium tweets if you want to filter?

Waiting to hear some more detail from the OP.  

Do you use some absorbing panels?

Do your ears hurt after listening?

Do you listen at 70dB or 85?